Long COVID Treatment – Vitamin B12, Vitamin D and other vital nutrients

Long COVID and COVID Long Haulers

COVID has gripped many lives for more than a year now and in some countries, people with Long COVID are lucky enough to be treated with essential nutrients which the virus appears to deplete or to exacerbate a latent deficiency. 

So many are writing about this and I wanted to collect together some of these texts for those unaware of a potential way back to full health.

 

The UK

Unfortunately many people in the UK with Long COVID may only be accessing the following treatments: aspirin, steroids, antivirals, antibiotics, and anti inflammatories as detailed on the Patient info website.

This BBC news clip on the effects of #longCOVID (and the following two) feature: Dr Nathalie Mac Dermott, Louise Buxton and Sarah Wakefield, who may benefit from the information within this blog, so if you know them, please share.

You will see that the symptoms of B12 deficiency (and other nutrient deficiencies) and Long COVID very much overlap:

Long-term COVID-19 Symptoms in a Large Un-selected Population.

“The long-term symptoms most enriched in those with COVID-19 are anosmia, ageusia, difficulty concentrating, dyspnea, memory loss, confusion, headache, heart palpitations, chest pain, pain with deep breaths, dizziness, and tachycardia.” 

In my April blog it was also highlighted that B12 could be of help in treating COVID and since then more information has been gathered.

I hope the following offers an added pathway back to health for those experiencing the debilitating effects of Long COVID.

New to Vitamin B12 Deficiency?

If you read the following documents and feel that B12 deficiency could be affecting you, then if possible, please try not to supplement with B12 before testing. Then please see this crash course for more info on how to diagnose and treat B12 deficiency.

You may need B12 injections if you cannot absorb B12 from food and even very low dose B12 tablets can raise serum B12 levels to be ‘within range’ which may skew results and stop you accessing the treatment you need. Some countries allow purchase of injectable B12 from pharmacies but for those in countries like the UK that currently don’t allow this (which we want to change) then you may need a doctor to diagnose and then treat you with injections.

If you have already tried oral B12 supplements but your symptoms haven’t improved, make sure you ask for testing and let the doctor know to make sure the lab note that you have been taking B12. Do not wait to be clear of supplements for 4 months, there is absolutely no point in wasting time!

It’s key that your doctor understands that a within range result, coupled with symptoms should not be ignored as the clinical picture is of utmost importance. Make sure you get to see a copy of your results – you are legally entitled to them.

 

In the UK the NHS stated that Long COVID sufferers would be offered help at specialist centres:

Respiratory consultants, physiotherapists, other specialists and GPs will all help assess, diagnose and treat thousands of sufferers who have reported symptoms ranging from breathlessness, chronic fatigue, “brain fog”, anxiety and stress.

Perhaps NHS England and Professor Chris Brightling would benefit from the information in this blog?


Hypotheses and articles on Long COVID treatment 

 

Sally Pacholok

Undiagnosed Cobalamin Deficiency in the Face of COVID-19:  An unrecognized Comorbidity and Silent killer.

“People with undiagnosed vitamin B12 deficiency may be at a higher risk of dying from COVID-19. Not only does low B12 suppress one’s immune system making it harder to fend off infection and produce antibodies, but B12 deficiency also causes hyperhomocysteinemia, which in turn can cause dangerous blood clots (i.e. deep vein thrombosis, pulmonary embolism, stroke, and myocardial infarction).”

Dr Albert Mir

Please see Dr Albert Mir’s Hypothesis Jan 2021 version –
COVID-19 and vitamin B12. An important warning for the population.                          

COVID-19’s toll on the elderly and those with diabetes mellitus – Is vitamin B12 deficiency an accomplice?

“…The question on hand thus lies on whether managing B12 deficiencies will impact COVID-19 fatality outcome or recovery rates. Herein, we review the latest evidence that shows that B12 deficiency associates in multiple areas very similar to where COVID-19 exerts its damaging effects: immunologically; microbiologically; haematologically; and through endothelial cell signalling—supporting the hypothesis that B12 deficiency is a potential modifiable risk factor in our fight against COVID-19.”

Be well: A potential role for Vitamin B in COVID-19

“There is a need to highlight the importance of vitamin B because it plays a pivotal role in cell functioning, energy metabolism, and proper immune function []. Vitamin B assists in proper activation of both the innate and adaptive immune responses, reduces pro-inflammatory cytokine levels, improves respiratory function, maintains endothelial integrity, prevents hypercoagulability and can reduce the length of stay in hospital [,]. Therefore, vitamin B status should be assessed in COVID-19 patients and vitamin B could be used as a non-pharmaceutical adjunct to current treatments.”

Vitamin b12 Deficiency in Covid-19 Recovered Patients: Case Report.

“The link between immunity and nourishment is clearly known and special attention is being given to its role in the COVID-19 disease Vitamin B12 is one of the dietary requirements necessary in the treatment of coronavirus patients Coronavirus patients often show clinical symptoms, such as fever, cough, respiratory distress syndrome, gastrointestinal infection, and fatigue It is sensible to suppose that COVID-19 affects cobalamin metabolism, impairs intestinal microbial proliferation, and contributes to symptoms of cobalamin deficiency Such an assumption is based on the fact that there are signs and symptoms of vitamin B12 deficiency that are similar to those of a coronavirus infection Based on these observations, it can be inferred that treatment with vitamin B12 can be useful in the recovery of COVID-19 patient.”       

A potential Role for Vitamin B in COVID-19.

“However, SARS-CoV-2 could interfere with vitamin B12 metabolism, thus impairing intestinal microbial proliferation. Given that, it is plausible that symptoms of vitamin B12 deficiency are close to COVID-19 infection such as elevated oxidative stress and lactate dehydrogenase, hyperhomocysteinemia, coagulation cascade activation, vasoconstriction and renal and pulmonary vasculopathy. In addition, B12 deficiency can result in disorders of the respiratory, gastrointestinal and central nervous systems. Surprisingly, a recent study showed that methylcobalamin supplements have the potential to reduce COVID-19-related organ damage and symptoms.”                                                                                                                                                      

ERYTHROCYTES AS A TARGET OF SARS COV-2 IN PATHOGENESIS OF COVID-19

“Hemolytic anemia in COVID-19, which develops at the first stage as a reaction to the SARS COV-2 viral microorganisms, causes cascading reactions to toxic erythropoietin and hemoglobin released from erythrocytes in the bloodstream, and then to hemosiderin released due to the death of erythrocytes in the tissue. The process ends with a decrease in the synthesis of erythropoietin in the decaying liver and kidneys, in the absence of the necessary vitamin B12 due to the pathology of its secretion in the gastrointestinal tract. The characteristic signs of damage to red blood cells in conditions of infection with COVID-19 indicate disruption of erythropoiesis, with developing iron deficiency and B12 anemia.”   

Homocysteine as a Potential Predictor of Cardiovascular Risk in Patients with COVID-19.

“Since the beginning of the novel coronavirus pandemic, the scientific community is in urgent need for reliable biomarkers related to disease progression, in order to early identify high risk patients. In fact, the rapid disease spread makes it necessary to divide patients in risk categories immediately after diagnosis, to ensure an optimal resource allocation. The identification of new biomarkers is strictly related to the understanding of viral pathogenetic mechanisms, as well as cellular and organ damage. Trustworthy biomarkers would be helpful for screening, clinical management and prevention of serious complications.” 

Can Vitamin B12 be an Adjuvant to COVID-19 treatment? 

“COVID-19 has  become an international pandemic and is causing a  worldwide public health emergency; therefore, an effective treatment is urgently needed. The hypothesis is that Covid virus interferes with the cobalamin metabolism, causing  symptoms  of cobalamin deficiency.  This is  plausible to  infer,  because there  are symptoms  of vitamin  B12 deficiency  that  are similar  to  those of  COVID-19. These symptoms  include increase oxidative  stress, homocysteine concentration, activation of the  coagulation  cascade, thrombocytopenia, elevated lactate  dehydrogenase  (LDH), low reticulocyte count, intravascular coagulation thrombosis, vasoconstriction, renal and pulmonary vasculopathies, which can result in respiratory, gastrointestinal and central nervous system  disorders.  Research  shows  that  high doses of methylcobalamin  is the  treatment for  symptoms  of vitamin  B12 deficiency.  Thus, an  additional hypothesis  is that treatment with vitamin B12, especially methylcobalamin, would reduce Covid’s damage to infected patients. Hence, in this  review  article  it  is  suggested  that  methylcobalamin  (vitamin  B12)  may  serve  as  an  attenuator  to  COVID-19symptoms. Clinical studies are required to confirm this hypothesis.”                                                                                              

COVID19, COBALAMIN / B12 AND SEPSIS: A LEFT OF FIELD SOLUTION

“High dose parenteral Cobalamin as prophylaxis and treatment for Covid19 and Sepsis/ARDS.”                                                                                                                                        

Homocysteine and the SARS-CoV-2 Coronavirus – The X Factor of Severe Disease and Death.

“Homocysteine (Hcy) is a natural, non-essential amino acid formed by the de-methylation of methionine. Pathologic elevations occur in many chronic conditions, particularly the cardiovascular conditions common with aging, and in SARS-Cov2. The most common co-existing morbidities, hypertension, cardiovascular disease, and diabetes are all strongly associated with elevated levels of Homocysteine.”
    

Vitamin C, D, Folate (B9), magnesium, zinc etc.

Jerome Burne’s blog 12 Dec 2020  Pressure rises for Vitamin supplements to protect against the virus.

“For almost a year now the government and the NHS have been studiously ignoring the possibility that a highly plausible way of effectively combating the virus would be to ensure that everyone, especially those most exposed to it, had adequate levels of the nutrients vital for a well-functioning immune system, such as Vitamin D, Vitamin C, zinc and selenium. Now suddenly three things that might just make a difference, have all happened at once…”

And the following papers:

Possible Treatments for Covid-19 or LongCovid.

Topic: Which vitamins, minerals, and health supplements might help people who have suffered from Covid-19 and its aftermath for too long?                       

SARS-Cov-2/Covid/19 ADULT RESPIRATORY DISTRESS SYNDROME /ARDS: HIGH DOSE IV METHYLCOBALAMIN IS A SAFE & COST EFFECTIVE RESCUE TREATMENT for ARDS

“Abstract -A SAFE AND EFFICACIOUS PROPHYLACTIC /TREATMENT FOR COVID19, TO PREVENT AND TREAT ACUTE RESPIRATORY DISTRESS SYNDROME, ALREADY EXISTS: RESPECTIVELY using HIGH DOSE IM AND IV METHYLCOBALAMIN FORM OF VITAMIN B12. The hydroxocobalamin form of B12 has been used in ICUs in France, Italy and China for nearly 70 years, as the anti-CN antidote of choice. It is safe, licensed and available. Methylcobalamin would be preferable, for a number of research based reasons. But both could be life savers in the current health crisis.”                                                           

The Role of Folic Acid in the Management of Respiratory Disease Caused by COVID-19.

“Entrance of coronavirus into cells happens through the spike proteins on the virus surface, for which the spike protein should be cleaved into S1 and S2 domains. This cleavage is mediated by furin, which can specifically cleave Arg-X-X-Arg sites of the substrates. Furin, a member of proprotein convertases family, is moved from the trans-Golgi network to the cell membrane and activates many precursor proteins. A number of pathological conditions such as atherosclerosis, cancer, and viral infectious diseases, are linked with the impaired activity of this enzyme. Despite the urgent need to control COVID-19, no approved treatment is currently known. Here, folic acid (folate), a water-soluble B vitamin, is introduced for the first time for the inhibition of furin activity. As such, folic acid, as a safe drug, may help to prevent or alleviate the respiratory involvement associated with COVID-19.”

Virtual Screening and Repurposing of FDA Approved Drugs Against COVID-19 Main Protease.

“The present study provided a comprehensive targeting of the first resolved COVID+19 structure of Mpro and found a suitable save drugs for repurposing against the viral Mpro. Ribavirin, telbivudine, vitamin B12 and nicotinamide can be combined and used for COVID treatment. This initiative relocates already marketed and approved safe drugs for potential use in COVID-treatment.”                                                                                                                                   

Clinical Trials are Proving that Vitamin D fights COVID-19 in Hospitals.    

Open Access Review Evidence Regarding Vitamin D and Risk of COVID-19 and Its Severity.

“Vitamin D deficiency co-exists in patients with COVID-19. At this time, dark skin color, increased age, the presence of pre-existing illnesses and vitamin D deficiency are features of severe COVID disease. Of these, only vitamin D deficiency is modifiable. Through its interactions with a multitude of cells, vitamin D may have several ways to reduce the risk of acute respiratory tract infections and COVID-19: reducing the survival and replication of viruses, reducing risk of inflammatory cytokine production, increasing angiotensin-converting enzyme 2 concentrations, and maintaining endothelial integrity. Fourteen observational studies offer evidence that serum 25-hydroxyvitamin D concentrations are inversely correlated with the incidence or severity of COVID-19. The evidence to date generally satisfies Hill’s criteria for causality in a biological system, namely, strength of association, consistency, temporality, biological gradient, plausibility (e.g., mechanisms), and coherence, although experimental verification is lacking. Thus, the evidence seems strong enough that people and physicians can use or recommend vitamin D supplements to prevent or treat COVID-19 in light of their safety and wide therapeutic window. In view of public health policy, however, results of large-scale vitamin D randomized controlled trials are required and are currently in progress.”                                                                  

Casting Sunlight on an Epidemic   Is vitamin D a critical host factor to prevent COVID-19?

“Some people will experience minimal effects from COVID-19 because their immune system can efficiently fight off the infection. The “host” factors that promote such a strong immune system were extensively studied before the age of antibiotics, and without an effective vaccine, they should be an important part of today’s response to the epidemic. Host factors that are often considered include vitamins (e.g., A and C), minerals (e.g., zinc and magnesium), and the omega-3 fatty acids. Of these, perhaps the most studied and most important host factor impacting survival from COVID-19 is vitamin D, created in skin from exposure to ultraviolet B radiation in sunlight.”                                                                              https://www.medpagetoday.com/infectiousdisease/covid19/85596

Vitamin D is the Solution to the Covid-19 Second Wave.

“What is causing the Second Wave? Vitamin D blood levels are seasonal; they rise and fall from one season to another. In summer, vitamin D levels are higher because people are out in the sunshine. When sunshine (specifically UV-B) strikes the skin, the body makes vitamin D. But as people spend more time indoors, in autumn and winter, vitamin D blood levels fall. The levels decrease from late September to October to November, and they reach their lowest extent in December through March.”                                                                               

Role of Vitamin D in Preventing of COVID-19 Infection, Progression and Severity.

“The outbreak of COVID-19 has created a global public health crisis. Little is known about the protective factors of this infection. Therefore, preventive health measures that can reduce the risk of infection, progression and severity are desperately needed. This review discussed the possible roles of  vitamin D in reducing the risk of COVID-19 and other acute respiratory tract infections and severity.”                                                                                    

Immune-boosting Role of Vitamins D, C, E, Zinc, Selenium and Omega-3 Fatty Acids: Could they Help Against COVID-19?

“Recent evidence has highlighted that nutritional supplementation could play a supportive role in COVID-19 patients. Administration of higher than recommended daily doses of nutrients such as vitamins D, C, E, Zinc and omega-3 fatty acids might have a beneficial effect, potentially reducing SARS-CoV-2 viral load and length of hospitalization . These nutrients are well-known for their antioxidant properties and immunomodulatory effects. Deficiencies in these nutrients can result in immune dysfunction, and increase susceptibility to pathological infection. In fact, dietary insufficiency of vitamins and minerals has been observed in high-risk groups of COVID-19 patients, such as the elderly, increasing the morbidity and risk of mortality  It is well known that the elderly are more likely to be nutrient deficient and to have compromised immunity via immuno-senescence, significantly increasing their risk of poor outcomes from COVID-19, and making adequate nutrition doubly important. The role of vitamins D, C, E, Zinc, selenium and omega-3 fatty acids in immunity, their status in patient infected by SARS-CoV-2 and their potential therapeutic role are discussed.”                                                                                                      

Nutrition, immunity and COVID-19.

“Vitamins B6 and B12 and folate all support the activity of natural killer cells and CD8+ cytotoxic T lymphocytes, effects which would be important in antiviral defence. Patients with vitamin B12 deficiency had low blood numbers of CD8+ T lymphocytes and low natural killer cell activity.”                                                                                                                                

Nutritional Status of Patients with COVID-19.

“Nutrients play a vital role in the defense against infectious diseases and the regulation of inflammation; however, little is known with regards to COVID-19.

We measured concentrations of vitamins B1, B6, B12, folate, vitamin D (25-hydroxyvitamin D), selenium, and zinc in 50 patients with COVID-19. Vitamin D deficiency was shown in 76% of patients and selenium deficiency in 42%. There was a significant difference compared to a control group of 150 people (vitamin D deficiency 43.3%). Among 12 patients with respiratory distress, 11 (91.7%) had one or more nutrient deficiency.”                                                                                                                                    

Combating COVID-19 and Building Immune Resilience: A Potential Role for Magnesium Nutrition? 

“In December 2019, the viral pandemic of respiratory illness caused by COVID-19 began sweeping its way across the globe. Several aspects of this infectious disease mimic metabolic events shown to occur during latent subclinical magnesium deficiency. Hypomagnesemia is a relatively common clinical occurrence that often goes unrecognized since magnesium levels are rarely monitored in the clinical setting. Magnesium is the second most abundant intracellular cation after potassium. It is involved in >600 enzymatic reactions in the body, including those contributing to the exaggerated immune and inflammatory responses exhibited by COVID-19 patients.”                          

A Cohort Study to Evaluate the Effect of Combination Vitamin D, Magnesium and Vitamin B12 (DMB) on Progression to Severe Outcome in Older COVID-19 Patients.

“Objective: To determine the clinical outcomes of older COVID-19 patients who received DMB compared to those who did not. We hypothesized that fewer patients administered 2DMB would require oxygen therapy and/or intensive care support than those who did not.”

____________________________________________________________________                                                                                                          

There are many more documents, papers and articles on nutrient deficiencies and COVID treatment and I hope this blog helps with your personal research and pathway to recovery.

I you wish to add any other articles to the comments please do, I would love to hear from you.

Kindness always

Tracey x

www.b12deficiency.info

Do you want to help make B12 injections available OTC from Pharmacies in the UK?

 

 

Petition update – Your help is needed for the next stage!

Petition response

We’ve had a response to our petition from the Department of Health and unfortunately they have reported what we already know about the regulations for a POM (Prescription only medicine).

They state that we can’t have injectable B12 made available from pharmacies in the UK because of the Human Medicines Regulation 62 section 3.

Westminster Hall Debate

This doesn’t mean we give up. This means we keep on going and thankfully My MP, Jane Hunt is committed to helping and will be making an application for a debate on our petition in Westminster Hall. The focus of this will be that the MHRA allow B12 injections to be given as a boost via hair salons and clinics. More on this in the next blog.

Your MP can help

We need your MP to speak for you, alongside Jane when this happens.

Please ask your MP to come on board, to make a speech on your behalf and get in touch with Jane so that they can work together on this.

Find your MP here: https://members.parliament.uk/FindYourMP

So if you feel strongly about being in control of your own health …

If you have had B12 injections stopped due to COVID…

If you are restricted to 3 monthly injections but need them more frequently…

If you feel you have no choice but to buy B12 from abroad because you can’t access what you need from your GP then please help to make this happen…

Here’s how you can help

I’ve added a draft email for you to use and adapt below so that you can easily send a message to ask your MP to help. It would be lovely to hear of their interest in this, so if possible please let me know by commenting on the blog.

Thank you so much for being part of this, I feel sure that if we keep working together we can make this important change happen.

Together I’m sure we can make this happen.

Kindness always

Tracey Witty

www.b12deficiency.info

Draft email 

Dear

Please can I ask for your support in making injectable vitamin B12 available OTC from pharmacies.

Following a reading of this petition at the House of Commons on the 23rd of September 2020 the Department of Health responded: They state that we can’t have injectable B12 made available from pharmacies in the UK because of the Human Medicines Regulation 62 section 3.

Jane Hunt MP is making an application for a Westminster Hall Debate on this petition and she needs your help.

This issue is really important to me because………………………….

Please contact Jane Hunt MP ( jane.hunt.mp@parliament.uk ) and get involved on my behalf.

Yours faithfully

If you can’t copy the above please find a copy of the text here

 

 

B12 Awareness Day 2020 In the House of Commons

I am delighted to announce that MP Jane Hunt will present a petition to the House of Commons today, Wednesday the 23rd of September 2020, which asks for injectable vitamin B12 to be made available over the counter from pharmacies.

Please note this is my New Government Petition and NOT the Change.org petition.

If your MP also has an interest in this issue, please ask them to come on board and help us to get this passed.

Jane is scheduled to present the petition titled “Removing classification of prescription only medicine from injectable vitamin B12,” at the end of the day just before the adjournment debate, usually around 7pm. There is no precise time yet but you will be able to watch it live on Parliament TV or on BBC Parliament.

The full petition text will be also posted on House of Commons Hansard and the Government will need to respond to it. Too many people are restricted to just four vitamin B12 injections per year which is not enough to heal damaged nerves.

All we can do now is sit and wait for a positive outcome which would bring us into line with many other countries who do allow injectable B12 to be purchased over the counter. This has the potential to make treatment of vitamin B12 deficiency free from stress and anxiety for millions of UK citizens, affording us the same level of dignity and control over our own health as a diabetic injecting insulin.

Huge thanks to everyone who has supported this movement and to MP Jane Hunt and her team for making this possible and for for caring about people with B12 deficiency.

I have everything crossed and I’m you sure you do too.

Kindness always

Tracey x
www.b12deficiency.info

Thank YOU for your kindness in sharing this post. You can buy your “B12 for life” campaign pin here.

 

Incontinence in women, men & children

One of my symptoms of B12 deficiency was bladder incontinence, I had to keep going to the loo and there was no let up during the small hours either.

Thankfully this was one of my symptoms which corrected within the first weeks of regular B12 injections. Had I not realised I was B12 deficient, I may have believed it was due to my age or my shoe size or my eye colour and perhaps even ‘perfectly normal’. Some of us have difficulty seeking help for incontinence and see it as something to ‘put up with’ rather than something that could and should be treated.

Each time I see TV adverts for companies selling incontinence pads (or those weird ‘pretty??!’ crepe britches) showing young women stating that incontinence is ‘perfectly normal’ I’ll ask the telly, “what if it’s caused by B12 deficiency?”

Apparently 1 in 3 women experience bladder leaks, this is a massive number, some of whom might potentially be in need of B12 but may be unaware of low B12 being a cause.

This report from the BBC shows that the Royal College of Nursing (RCN) has issues with these adverts. They criticised TENA for not highlighting to mothers that treatment for the condition is available.

The RCN said: “Incontinence is known to be under reported due to the embarrassment experienced by women living with the condition.

Female incontinence
As you’ll see from the information on the NHS link below, there are a few causes for bladder incontinence related to the pelvic floor muscles, and although they do list ‘neurological conditions that affect the brain and spinal cord such as Parkinson’s disease or multiple sclerosis’  –  just think how helpful it would be if they could alert people by adding B12 deficiency to this list?

  • damage during childbirth – particularly if your baby was born vaginally, rather than by caesarean section
  • increased pressure on your tummy – for example, because you are pregnant or obese
  • damage to the bladder or nearby area during surgery – such as the removal of the womb (hysterectomy), or removal of the prostate gland
  • neurological conditions that affect the brain and spinal cord, such as Parkinson’s disease or multiple sclerosis
  • certain connective tissue disorders such as Ehlers-Danlos syndrome
  • certain medicines

Male Incontinence
Men also experience incontinence and it’s no surprise that they are even worse than women for talking about it or seeking help. Naturally there are some different causes listed for males (please see below), but would it be on the radar of the GP to test for B12 deficiency even if the subject of incontinence arose at an appointment?

  • chronic cough
  • constipation
  • obesity
  • bladder or urinary tract infections
  • an obstruction in the urinary tract
  • weak pelvic floor or bladder muscles
  • loss of sphincter strength
  • nerve damage
  • enlarged prostate
  • prostate cancer
  • neurological disorders, which can interfere with bladder control signals

Other lifestyle factors that may lead to UI include:

  • smoking
  • drinking
  • not being physically active

When you can’t remember where you live, or who loves you…..

Our poster boy Jasper has been showing the signs of his advancing years.  He was a rescue so we can’t be sure how exactly how old he is, but he’s at least fifteen.

His eyesight and hearing have been deteriorating for a while so we clap to get his attention. People seeing this think we are congratulating him rather that trying to communicate where we are!

A few weeks ago he suddenly stopped being interested in food, he was noticeably confused, he stopped barking, or making any sound at all.

 

dooby-b12-text-version

He has always loved a particular fluffy sheep toy but he no longer recognised this previously constant companion.

He wanted to be outside a lot, but then could not find his way back in, he would stand in one spot under a tree or would stare at the wall vacantly. He failed to recognise us.

His eating habits completely changed and some days he turned his nose up at everything offered. His co-ordination was also affected and at times he struggled to stand up.

He was very distant and for a normally loving and friendly dog this was a real shock.

Three weeks ago our vet came out to assess him and check he was not in any pain and confirmed he was showing signs of senility.

The first thing the did, was give him a B12 injection.  Stating that he could have these when required.

The following two days were much the same as before but on the third day, we were astounded. He wanted to eat, he was happy, he had stopped wanting to be apart from us, he barked and found and chewed on his old friend the sheep!!  He still moves like an elderly dog, he still can’t see or hear too much – but the essence of him is back.

Of course B12 is not the answer to every ill. It is however essential to life and for those who are deficient, whose systems have been starved of it, it can have a miraculously swift effect. This is what B12 does for those of us in need, it gives us our essence back.

Don’t all dementia patients deserve this chance, before it’s too late – just in case?

B12 deficiency is very common in the older population, for many reasons; one being low stomach acid, not helped by the over medication of PPI’s and other acid suppressants.

There is no routine screening of so many at risk patients and too many elderly B12 deficient patients may be missed when there are guidelines for doctors like these below;

Wouldn’t it be lovely if our doctors were not constrained by such ridiculous and out dated instruction?

The name ‘Pernicious anaemia’ confuses doctors – many patients NEVER present with anaemia/macrocytosis – this is very late stage. NICE and BNF Guidelines still categorise B12 deficiency under anaemia and this needs to change.

Thankfully our vet did not have to concern himself with proving Jasper was anaemic, he didn’t have to wait for a B12 serum test, he knew that this kind of presentation in an elderly dog could be down to B12 deficiency and his injection was given without any hesitation. He can also have B12 injections regularly without any quibbling.

If only B12 deficient humans, of any age, could be treated in the same sensible way as this little old fella, the world for them would be so much less confusing.

For those who may be B12 deficient please see this page;  www.b12deficiency.info/what-to-do-next/

If you feel strongly about the restrictions on our B12 treatment please sign and share this petition

www.change.org/p/ian-hudson-please-make-our-life-saving-injectable-vitamin-b12-hydroxocobalamin-available-over-the-counter

Best wishes

Tracey